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Anti Inflammation and Anti Oxidant Effect of Active Agent Polysaccharide Peptide (Ganoderma Lucidum) in Preventing Atherosclerotic Diseases. Sargowo D, Prasetya I, Ashriyah R, Setyawati I, Andri W.
Polysaccharide peptide ( Ganoderma lucidum) anti-inflammation anti oxidant cardiovascular disease atherosclerosisĭownload this article as: Copy the following to cite this article:
ANTI INFLAMMATION DIET FOR DUMMIES PDF PSP
PSP can be useful to reduce inflammatory processes and oxidative stress to prevent atherogenesis. The formation of foam cells (p=0.024) as a marker of atherogenesis significantly decreased by administration of PsP. PsP improve the lipid profile by increasing HDL (p=0.002) and lowering total cholesterol (p=0.04). While the levels of TNF-α (p=0.894) and IL-10 (p=0.98) was not affected by administration of PsP. PsP can reduce levels of IL - 6 (p=0.933) and increase levels of SOD (p=0.28) descriptively at PsP doses 150 mg/kgBW. After PsP therapy for 5 weeks, the levels of MDA (p=0.01), hsCRP (p=0.018) in rats model of atherosclerosis decrease significantly. Parameters measured were the level of MDA, SOD, IL - 6, IL - 10, hsCRP, TNF - α, lipid profile and foam cell. The atherosclerotic rats were randomly divided into four groups (5 rats each group) : atherosclerotic model with high-fat diet, low dose PsP treated group (50 mg/kgBW), medium dose PsP treated group (150 mg/kgBW), high dose PsP treated group (300 mg/kgBW), with normal mice used as a control group. This study was aimed to evaluate anti-inflammatory and antioxidant effect of polysaccharide peptide (PsP) from Ganoderma lucidum in atherosclerosis. Saiful Anwar Hospital, Malang. Jaksa Agung Suprapto Street, no. Zainoel Abidin Hospital, Banda AcehĤDepartment of Internal Medicine, Faculty of Medicine, Brawijaya University / Dr. Saiful Anwar Hospital, MalangĢDepartment of Nursery, Faculty of Medicine, Brawijaya University, MalangģDepartment of Cardiology and Vascular Medicine, Faculty of Medicine, Syiah Kuala University / Dr. Djanggan Sargowo 1,4, Indra Prasetya 1, Ria Ashriyah 1, Ira Setyawati 1, W Titin Andri 2, Teuku Heriansyah 3ġDepartment of Cardiology and Vascular Medicine, Faculty of Medicine, Brawijaya University / Dr.
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